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Original Article
NT-proBNP as a useful tool in diagnosing incomplete Kawasaki disease
Dong Won Lee, Yeo Hyang Kim, Myung Chul Hyun, Tae Chan Kwon, Sang Bum Lee
Clin Exp Pediatr. 2010;53(4):519-524.   Published online April 15, 2010
Purpose : To determine the efficacy of the N-terminal fragment of B-type natriuretic peptide (NT-proBNP) as a useful diagnostic method in children with incomplete Kawasaki disease (KD). Methods : Ninety-six patients who were diagnosed as having KD between January 2008 and June 2009 were enrolled in the study. American Heart Association recommendations for diagnosis were used, and patients were divided into...
Case Report
Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction
Ji Hyeun Song, Yeo Hyang Kim, Chun Soo Kim, Sang Lak Lee, Tae Chan Kwon
Clin Exp Pediatr. 2009;52(1):129-132.   Published online January 15, 2009
We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiomegaly, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered...
Original Article
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Joon Sung Lee, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2008;51(12):1320-1323.   Published online December 15, 2008
Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age. Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6...
Case Report
Supraventricular tachycardia in a neonate with cardiac rhabdomyoma and tuberous sclerosis
In Kug Bang, Yeo Hyang Kim, Chun Soo Kim, Sang Lak Lee, Tae Chan Kwon
Clin Exp Pediatr. 2008;51(7):766-770.   Published online July 15, 2008
Primary tumors of the heart are uncommon among pediatric patients. Rhabdomyoma is the most frequent cardiac tumor in infants and children, which is commonly associated with tuberous sclerosis. Tuberous sclerosis is a neurocutaneous syndrome affecting the brain, heart, skin, and other organs. Cardiac rhadomyomas are reported in 50-64% of infants with tuberous sclerosis. Tuberous sclerosis involves multiple locations in the...
A case of recurrent hepatoblastoma : lung, heart and brain metastasis
Sun Mi Park, Byung Kyu Choe, Yeo Hyang Kim, Heung Sik Kim, Tae Chan Kwon, Hee Jung Lee
Clin Exp Pediatr. 2006;49(6):691-695.   Published online June 15, 2006
Hepatoblastoma is a hepatic tumor predominantly occurring in children. The usual site of metastasis is the lung. There are only several reports worldwide on the distant metastasis of hepatoblastoma to the central nervous system in children. Only one reported case showed survival of a patient after multiple resections of a recurrent brain lesion. Involvement of the cardiovascular system has been...
Original Article
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2005;48(10):1139-1142.   Published online October 15, 2005
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of...
Case Report
A Case of Weaver Syndrome
Jun Chul Byun, Chun Soo Kim, Sang Lak Lee, Tae Chan Kwon, Hee Jung Lee
Clin Exp Pediatr. 2004;47(11):1216-1219.   Published online November 15, 2004
Weaver syndrome is a very rare overgrowth syndrome with accelerated skeletal maturation, unusual facies and clinodactyly. We experienced an extremely rare case of Weaver syndrome in Korea. The clinical manifestations were macrocephaly, unusal facies, simian crease, clinodactyly, decreased muscle tone, accelerated bone age and congenital heart diseases. We report this with a brief review of related literature.
Original Article
Clinical Manifestation and Associated Cardiac Anomalies of Dextrocardia
Sung Hoon Kim, Seung A Hong, Yoon Jung Cho, Sang Lak Lee, Tae Chan Kwon
Clin Exp Pediatr. 2002;45(5):622-628.   Published online May 15, 2002
Purpose : The purpose of this study is to ascertain the clinical manifestations and associated cardiac anomalies of dextrocardia. Methods : Twenty-four pediatric patients, who were admitted to, or visited, Dongsan Medical Center Keimyung University and were diagnosed with dextrocardia between January 1996 and July 2001, were enrolled in this study. All patients received echocardiogram and abdominal ultrasonogram to identify...
Case Report
A Neonatal Case of Symptomatic Congenital Cytomegalovirus Infection with Hearing Defect
Sung Jun Jang, Yoon Jung Cho, Sang Lak Lee, Joon Sik Kim, Tae Chan Kwon
Clin Exp Pediatr. 2001;44(2):205-210.   Published online February 15, 2001
Cytomegalovirus(CMV) is one of the leading cause of intrauterine infections of man with an incidence ranging from 0.48% to 2.2% of all live births. Although the majority of CMV-infected newborns are clinically asymptomatic at birth, some will have signs of congenital infection : Intrauterine growth retardation, petechial or purpuric rash, microcephaly, anemia, thrombocytopenia, jaundice, hepatosplenomegaly and intracranial calcification. We experienced...
Original Article
Incidence of Congenital Heart Disease in Neonate by Color Doppler Echocardiography
Tae Chan Kwon, Joon Sik Kim, Sang Lak Lee, Myung Sung Kim, Geun Soo Park, Chun Soo Kim, In Joo Kim, Bin Ahn
Clin Exp Pediatr. 1998;41(3):363-368.   Published online March 15, 1998
Purpose : Many reports exist about the frequency of congenital heart disease(CHD) in the world, but according to the definition of CHD and subjects of study group, many differences existed between the reports. We conducted this study to evaluate the incidence and frequency of CHD by color Doppler echocardiography in neonate, and to suggest a preliminary model of incidence of...
Case Report
A Case of Ectopia Cordis
Sun A Kim, Chun Soo Kim, Geun Soo Park, Myung Sung Kim, Sang Lak Lee, Joon Sik Kim, Tae Chan Kwon
Clin Exp Pediatr. 1997;40(3):413-416.   Published online March 15, 1997
Ectopia cordis is a very rare cardiac anomaly that the heart is partially or totally outside the thorax, and it was classified anatomically as 5 types-cervical, thoracocervical, thoracic (most commontype), thoracoabdominal, abdominal types. We experienced a case of ectopia cordis(thoracic type) in a newborn who had the symptom of generalized cyanosis since birth, and expired during operation due to recurrent bradycardia and hypotension. The brief...
Original Article
Normal Values of Left Ventricular Mass by Echocardiography in Korean Children
Eun A Kim, Chun Soo Kim, Geun Soo Park, Myung Sung Kim, Sang Lak Lee, Joon Sik Kim, Tae Chan Kwon
Clin Exp Pediatr. 1996;39(6):797-802.   Published online June 15, 1996
Purpose : Determination of left ventricular myocardial mass with echocardiography is feasible and validated. American Society of Echocardiography(ASE) issued recommendations for the quantitation of the left ventricle by M-mode echocardiography. The purpose of this study is to determine the mean value of left ventricular mass in Korean children. Methods : We measured left ventricular mass in 498 subjects(male 289, female 209) using ASE...
Plasma Norepinephrine Levels in Infants and Children with Congestive Heart Failure
Sang Woog Lee, Myung Sung Kim, Sang Lak Lee, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1993;36(7):982-986.   Published online July 15, 1993
To characterize the sympathetic nervous system response to congestive heart failure in infants and children, plasma norepinephrine levels were measured in 29 patients aged 4 months to 15 years undergoing routine cardiac catheterization at Dong San Hospital, Keimyung University during the period of 4 months from November 1990 to February 1991. Plasma norepinephrine levels were significantly higher in patients with heart...
Case Report
A Case of Cor Triatriatum
Sung Jin Chang, Joon Sik Kim, Tae Chan Kwon, Chin Moon Kang, Kwan Soo Lee, Young Sun Yoo
Clin Exp Pediatr. 1992;35(7):1001-1007.   Published online July 15, 1992
Cor triatriatum is characterized by the presence in the left atrium of a perforated muscular membrane which separates the atrium into proximal and distal chambers. Authors experienced a case of cor triatriatum in a 20 month old boy. Diagnostic confirmation was made by 2-D echocardiography, cardiac catheterization completely excised. The postoperatative course was excellent.
Original Article
A Case of Interrupted Aortic Arch.
Yeong Sook Kang, Sun Hee Jung, Tae Chan Kwon, Chin Moo Kang, Seok Kil Zeon, Kwang Sook Lee, Yeong Sun Yoo
Clin Exp Pediatr. 1990;33(11):1579-1585.   Published online November 30, 1990
Interrupted aortic arch is a congenital anomaly in which discontinuity is present between ascending and descending aorta, and is associated frequently with ventricular septal defect and patent ductus arteriosus. Authors experienced a case of interrupted aortic arch in a 4 year old boy associated with a ventriculalr septal defect and patent ductus arteriosus. Diagnostic confirmation was made by 2-D echocardiography, cardiac cathetrization and angiogra- phy. Direct closure...
Correlation among Electrocardiographic, Echocardigraphic and Hemodynamic Analysis in Atrial Septal Defect, Ostium Secundum type.
Soon Jung Lee, Chi Han Kwon, Joon Sik Kim, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1990;33(7):946-951.   Published online July 31, 1990
The electrocardiographic, echocardiographic and hemodynamic analysis were made on 32 patients with atrial septal defect of ostium secundum type, who were diagnosed by echocardiography, right heart catheterization at Dong San Hospital, Keimyung University during the period of 5 years and 6 months from Jaunary 1982 to June 1987. Following results were obtained. Out of 32 patients, 14 were male and 18 were female. Their ages...
Comparisons of the Pressure Gradients between Two-Dimensional Echocardiographic Doppler Studies and Cardiac Catheterization in Pulmonary Stenosis.
Won Ho Choi, Young Sook Kang, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1990;33(7):940-945.   Published online July 31, 1990
The right ventricular outflow tract pressure gradient measured by Doppler echocardiography was compared with the pressure gradient by cardiac catheterization in 19 children who were admitted to the department of Pediatrics, Dong San Hospotal during the period of 18 months from January 1987 to June 1988 for the evaluation of heart disease. Among 19 cases, 10 cases were Tetralogy of Fallot, 5 cases were...
Clinical Study on Hypernatremic Dehydration in Children.
Young Mi Kim, Key Young Song, Sung Ho Kim, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1990;33(2):146-152.   Published online February 28, 1990
The clinical study was done on 68 cases of hypernatremic dehydration which were diagnosed at pediatric department of Dong-san Hospital Keimyung University during the period from January 1980 to June 1987. The results were as follows; 1) Among 672 cases with dehydration, hypernatremic dehydration was 10.1% 2) The higer monthly distribution was in May and November. 3) Out of 68 cases, 61 cases (89.7%) were under the 6 months...
The Collaborative Clinical Analysis of 985 Cases of Rheumatic Fever and Rheumatic Carditis in Children for 10 Years(1978~1987) in Korea.
Sung Ho Cha, Sang Young Jeong, Du Bong Lee, Kyong Su Lee, Sang Bum Lee, Tae Chan Kwon, Young Chang Tockgo, Chang Sung Sohn, Keun Chan Sohn, Young Jin Hong, Chan Young Kim, Chang Yee Hong, Yong Soo Yun, Jung Yun Choi, Chang Hwi Kim, Chul Ho Kim, Tae Ju Hwang, Jae Suk Ma, Chan Uhul Joo, Kyoo Hwan Rhee, Hahng Lee
Clin Exp Pediatr. 1989;32(12):1621-1631.   Published online December 31, 1989
Acute rheumatic fever and rheumatic carditis were still important disease of the acquired heart disease in children and adults, in spite of improving socioeconomic status in Korea. Recently, many outbreaks of acute rheumatic fever have been reported in the papers from developed countries. We should be aware of such outbreaks of acute rheumatic fever and should pay attention to their treatment of the patients...
The Hemodynamics and Electrocardiogram in Isolated Ventricular Septal Defect.
Kwang Man Kim, Ki Young Song, Sang Kwon Lee, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1989;32(8):1098-1105.   Published online August 31, 1989
Ventricular septal defect is the most common cardiac malformation, accounting for 25% of congenital heart disease. The electrocardiogram is becoming more useful as a tool in estimating the size of the ventricular septal defect and the type of pulmonary vascular response. This report comprises 210 patients in whom the diagnosis of isolated ventricular septal defect was made by cardiac catheterization and angiocardiography at Dong San...
Abdaninal Tumor in Infants and Children.
Young Soo Kim, Kwang Man Kim, Seung Ho Kim, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1989;32(3):366-374.   Published online March 31, 1989
Eighty seven patints with abdominal tumor which were diagnosed with abdominal C-T scan and confirmed histologically were reviewed. These patients were admitted to pediatric department of Dong San Medical Canter from January, 1980 to June, 1986. The results were as follows; Out of 87 patients, 30 (34.5%) were intraperitoneal and 57 (65.5%) were retroperitoneal tumor. Among intraperitoneal tumor, 15 cases (50%) were hepatosplenomegaly, and among...
Hydronephrosis in Children.
Jong Soo Lee, Dong Min Kang, Hong Dae Cha, Seong Ho Kim, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1988;31(3):322-328.   Published online March 31, 1988
Hydronephrosis is the commonest abdominal tumor in infants and children resulted from urinary tract obstruction. The urinary tract obstruction has been defined as a disturbance of the normal pressureflow relationships in the urinary tract and it is only by an increase in pressure that the effects of obstruction are transmitted back to the kidney. This report is a clinical study on 47 hydronephrosis under...
Clinical Analysis on Organisms Isolated from Blood Culture.
Dong Min Kang, Jong Seo Lee, Hong Dae Cha, Tae Chan Kwon, Chin Moo Kang
Clin Exp Pediatr. 1988;31(1):40-47.   Published online January 31, 1988
This is the report of clinical analysis on 197 organisms isolated from blood culture for 8,385 patients which were admitted to the Pediatric department of Dong San Hospital, Keimyung University, during the priod of 3 years from June 1982 to May 1985. The results were as follows Out of 197 cases, 81 (41.4%) were above 5 years of age. Out of 197 cases, 117 (59.4%)...
Case Report
A Case of Multiple Brain Abscess Complicated to Purulent Meningitis in Newborn.
Kui Ja Kim, Hye Young Chung, Tae Chan Kwon, Young Dae Kwon, Chin Moo Kang
Clin Exp Pediatr. 1983;26(7):717-721.   Published online July 31, 1983
This paper presented a case of multiple brain abscesses complicated with meningitis, found in a 7 days old newborn boy. This baby was admitted with the chief complaints of poor sucking and irritability. Diagnosis of purulent meningitis was made through CSF study. High fever and abnormal CSF(pleccytcsis and gradually increasing protein level) has been persisted inspite of broad spectrum heavy antibiotic...
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